Certified Surgical First Assistant (CSFA) Practice Test

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What is the most common type of liver cancer encountered in clinical practice?

Hepatocellular carcinoma
Cholangiocarcinoma
Metastatic disease
Angiosarcoma

The correct answer is: Metastatic disease

Hepatocellular carcinoma is recognized as the most prevalent form of primary liver cancer in clinical practice. It arises from the hepatocytes, which are the main functional cells of the liver. This cancer is often associated with chronic liver diseases such as hepatitis B and C infections and cirrhosis. Due to its common occurrence and significance in patients with underlying liver conditions, hepatocellular carcinoma is the type most frequently diagnosed among liver cancer cases. Cholangiocarcinoma, while significant, is less common than hepatocellular carcinoma and arises from the bile ducts. Metastatic disease refers to cancer that has spread to the liver from other parts of the body, which, although common, is not classified as a primary liver cancer. Angiosarcoma is a rare cancer that originates from the blood vessels in the liver and is not as frequently encountered compared to hepatocellular carcinoma.